Wilson disease occurs when your body retains copper. Wilson disease is a rare and inherited disorder. Our liver would normally release any copper that it does not need into bile. When a person has Wilson disease this does not happen. Copper will build up in your liver and injures liver tissue. The damage causes your liver to release the copper directly into your bloodstream. Then the blood carries copper all over your body. Too much copper can damage your kidneys, liver, brain and eyes.
The gene for Wilson's disease (ATP7B) is mapped to chromosome 13. The GeneID is 540.
The gene is associated with the P-type cation transport ATPase family and encodes a protein with membrane-spanning domains. The protein works by exporting copper out of the cells.
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