Obesity Disease

1. Obesity is an excess of body fat; doctors generally agree that men with more than 25% body fat and women with more than 30% are obese. Obesity is a known risk factor for chronic diseases including heart disease, diabetes, high blood pressure, stroke and some forms of cancer.
2. Gene Name: Leptin, GeneID: 3952, also known as OB; OBS; FLJ94114; LEP
3. This gene encodes a protein that is secreted by white adipocytes, and which plays a major role is the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass.